Cerebellum: granule cell migration and a Purkinje cell (rat, Golgi impregnation)
1. dendrite system of the *Purkinje cell, the dendritic spines are clearly visible
1. dendrite system of the *Purkinje cell, the dendritic spines are clearly visible
2. axon hillock
3. cell body (perikaryon) of the Bergmann glial cell
4. granule cells, migrating downwards on the the Bergmann glial fibers
4. granule cells, migrating downwards on the the Bergmann glial fibers
This slide was prepared from an immature cerebellum where the migration of the granule cells is still in progress. The cerebellar granule cells start their development in a so-called external granular
layer from which they descend, guided by the processes of the Bergmann glia, to their final destination. The granule cells gain their final maturity during this migration.
The Bergmann glia represents a special type of astro{glia}. The role of the glia as a guide for the migration of the neurons is a common phenomenon in the central nervous system.
The dendritic spines represent post{synaptic} elements.
From the research files of Dr. Zoltán Fülöp.